Clamp-On Ultrasonic Flow Meter

SONOFLOW® CO.55 V2.0 & V3.0

For Bioprocessing Applications

Measure flow accurately, without product contact. A SONOFLOW CO.55 series clamp-on ultrasonic flow meter offers non-invasive, real-time liquid flow monitoring for flexible tubing in biopharma, single-use systems, and GMP environments.

  • V2.0 delivers compact, transmitter-free performance for development and OEM use. Flow measurement from 20 mL/min.
  • V3.0 adds a built-in color touchscreen on stainless steel models for enhanced visibility and control — zero and perform other functions directly from the touchscreen. Flow measurement from 5 mL/min.

Both models use ultrasonic transit-time technology for precise, repeatable, and contamination-free monitoring — with wide tubing compatibility and real-world performance down to 5 mL/min.

sonoflow co.55 v2.0 portfolio sonotec

Compact. Modular. Integrator-friendly.

The V2.0 model is designed for upstream and downstream monitoring in the bioprocess industry. The innovative sensors have integrated electronics which allow them to function without an external board or transmitter, resulting in a compact flow meter in the size of a small transducer. The ultrasonic devices ensure scale-up from process development to commercial applications in GMP environments.

Highlights:

  • Reliable flow measurement from 20 mL to 200 L / min
  • Accuracy of up to 1 % when adjusted for customer specific tubing / fluid
  • Ideally suited for silicone, TPE, and most standard bioprocess tubing
  • Real-time flow measurement
  • Volume totalizing and dosing output switch
  • Integrated electronics, no external transmitter required
  • Stainless steel models offer built-in informational screen (no interactivity, for viewing flow rate and volume only)

sonoflow co.55 v3.0 portfolio sonotec

GMP-ready. Touchscreen enabled.

The V3.0 clamp-on ultrasonic flow meter combines outstanding measurement accuracy over a wide flow range and highest clamp-to-clamp repeatability. The compact SONOFLOW CO.55 V3.0 flow meters with integrated electronics are suitable for applications ranging from process development through GMP to fill and finish operations.

Highlights:

  • Reliable real-time flow measurement from 5 mL / min to 180 L / min
  • Measurement accuracy of 1% even at lowest flow rates
  • Excellent clamp-to-clamp repeatability for standard bioprocessing tubing
  • Non-contact design preventing any media contamination and shear stress on cells
  • GMP-friendly stainless steel housing with intuitive color touch display
  • Volume totalizing and dosing output switch
  • Stable measurement unaffected by bubbles and different pressure conditions
  • Configuration via SONOTEC software
  • Integrated electronics, no external transmitter required

Best for GMP manufacturing, fill/finish stations, labs needing local visual access.

Supports a wide range of standard tubing sizes from 1/32″ to 1″, including:

Tube ID (in)Tube OD (in)Compatible Sensor Models
1/325/32CO.55 / 035 V2.0
1/163/16CO.55 / 044 V2.0
1/81/4CO.55 / 0250 V3.0, CO.55 / 060 V2.0
1/161/4CO.55 / 0250 V3.0, CO.55 / 060 V2.0
3/163/8CO.55 / 0375 V3.0, CO.55 / 080 V2.0
1/43/8CO.55 / 0375 V3.0, CO.55 / 080 V2.0
5/167/16CO.55 / 0438 V3.0, CO.55 / 100 V2.0
1/47/16CO.55 / 0438 V3.0, CO.55 / 100 V2.0
5/161/2CO.55 / 0500 V3.0, CO.55 / 120 V2.0
1/41/2CO.55 / 0500 V3.0, CO.55 / 120 V2.0
3/89/16CO.55 / 120 V2.0
3/85/8CO.55 / 0625H V3.0, CO.55 / 140 V2.0
5/165/8CO.55 / 0625H V3.0, CO.55 / 140 V2.0
1/23/4CO.55 / 0750H V3.0, CO.55 / 160 V2.0
3/83/4CO.55 / 0750H V3.0, CO.55 / 160 V2.0
1/27/8CO.55 / 190 V2.0
5/87/8CO.55 / 190 V2.0
3/41CO.55 / 1000H V3.0, CO.55 / 230H V2.0
5/81CO.55 / 230H V2.0
3/41 1/8CO.55 / 1125H V3.0, CO.55 / 260H V2.0
3/41 1/4CO.55 / 300H V2.0
11 3/8CO.55 / 1375H V3.0, CO.55 / 340H V2.0


AccessoryDescriptionCompatible WithImage
SONOTEC SoftwareSensor configuration, calibration, real-time monitoring, and data loggingV2.0 & V3.0
USB Data ConverterProvides power and USB connection to SONOTEC Software; ideal for lab useV2.0 & V3.0
SONOFLOW Remote DisplayCompact external display with zeroing, volume reset, and unit switchingV2.0 & V3.0
Ethernet/IP GatewayConnects SONOFLOW sensors to industrial PLC systems via Ethernet/IPV2.0 & V3.0


UpstreamExample Use Cases
Media PrepReplacing scales for volume measurement
InoculationInjecting cell lines into the reactor
BioreactorFeeding media / nutrients, control flow into and out of the bioreactor and ATF filters
CentrifugationDetermining flow / no flow

DownstreamExample Use Cases
Buffer PrepReplacing scales for volume measurement
ChromatographyBalancing acid / base delivery to the system
FiltrationControlling process conditions during filtration
Tangential Flow FiltrationMeasuring flow rates on feed, permeate, or retentate lines
Fill / FinishMeasuring volume of fluid dispensed into containers

Precision made in Germany.

SONOTEC specializes in ultrasonic sensor technology for non-contact liquid flow measurement and air bubble detection. With a strong presence in biopharma and medical applications, SONOTEC delivers:

  • ISO 9001 and ISO 13485 certified manufacturing
  • ATEX / IECEx-ready options for explosive environments
  • Scalable sensor solutions from lab to GMP production

SONOTEC sensors are designed for system integration, continuous processing, and cleanroom compliance — ensuring high performance across the full bioprocess lifecycle.



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