Total Organic Carbon Monitoring Empowers Eco-Friendly Pharmaceutical Production

total organic carbon monitoring empowers eco-friendly pharma production

The Need for Water in Pharma Production, and Considerations of Water Scarcity The issue of water scarcity is on the rise, and this problem is becoming more prominent in various industries. Water plays a crucial role in nearly every aspect of production, including the pharmaceutical manufacturing sector, which relies heavily on significant water quantities. Concerns […]

Cell Capacitance Measurements: Aber Futura vs Hamilton Incyte Arc

cell capacitance measurements aber vs hamilton

Introduction When it comes to cell capacitance measurements, researchers and scientists rely on advanced instruments to obtain accurate and reliable data. In this blog post, we will compare two popular options: the Aber Futura and the Hamilton Incyte Arc. Both devices offer sophisticated features and promise precise results, but understanding their unique capabilities and differences […]

The Importance of a Calibrated Raman System

raman calibration

In the world of Raman spectroscopy, the game-changing impact of an analyzer cannot be understated. Across various industries – from pharmaceuticals and bioprocessing to plastics and polymers, these instruments help process environments streamline their decisions, create efficiencies across the supply chain, cut costs, and enhance product quality. Raman analyzers are no different than any other […]

Achieving Superior Raman Measurements: Understanding and Avoiding Detector Saturation

One of the primary technological advantages of Tornado Raman analyzers over conventional Raman devices is the significantly higher optical efficiency delivered by our HTVS™ platform (described in this prior blog post). With 10x to 30x more photons per second, Tornado systems provide superior spectral data for better precision and sensitivity for PAT measurements, as we […]

Raman as a PAT tool – Part 2: Crystallization Monitoring and Control

raman as a PAT tool part 2

In our previous blog, we provided a fundamental overview of Process Analytical Technology (PAT) and its application for various industries, including pharmaceutical and chemical manufacturing. To recap, there is an increasing demand for new approaches to understanding the chemical and physical phenomena that occur during manufacturing processes. Obtaining real-time information from processes opens new perspectives […]

Raman as a Process Analytical Technology (PAT) tool

raman as a process analytical technology (PAT) tool

Process Analytical Technology (PAT) has quickly become an integral component within the pharmaceutical and chemical manufacturing industries, providing timely quantitative measurements throughout production to measure critical quality attributes and parameters. In October 2004, the U.S. Food & Drug Administration (FDA) announced a Process Analytical Technology (PAT) approach for pharmaceutical manufacturers in their Guidance for Industry […]

Choosing the right laser for Raman spectroscopy

choosing the right laser for raman spectroscopy

In recent years, Raman spectroscopy has become a valuable tool in qualitative and quantitative chemical analysis for process analysis as the technology offers convenient in-situ sampling interfaces, continuous in-line measurements, and high spectral specificity. Raman is used across a range of industries including pharmaceuticals, oil & gas, bio processing, specialty chemical, food and beverage process […]

High Purity New England Supports Drug Development Pipelines with Fully Customizable and Flexible Single-Use Assembly Solution

HPNE supports drug development pipelines with fully customizable and flexible single use assembly solution

Demand for single-use assembly solutions in the biopharma industry continues to increase, with the market expected to be worth $26.89 billion by 20251 . To help meet that demand High Purity New England (HPNE), a leading supplier of biopharma equipment and process solutions for the biopharma industry, created HPConnexx, a single-use assembly solution suitable for […]

Dissolved CO2 Measurement in Cell Culture: Integrating an Inline CO2 Sensor

CO2 as a metabolic indicator Impact of CO2 on Extracellular and Intracellular pH Dissolved Carbon Dioxide Measurement & Control It has become industry practice to keep a close watch and refined control on pH and dissolved O2, in conjunction with parameters including pressure, temperature, and aeration rates. We’ve also seen a growing necessity to monitor […]