Raman as a PAT tool – Part 2: Crystallization Monitoring and Control

raman as a PAT tool part 2

In our previous blog, we provided a fundamental overview of Process Analytical Technology (PAT) and its application for various industries, including pharmaceutical and chemical manufacturing. To recap, there is an increasing demand for new approaches to understanding the chemical and physical phenomena that occur during manufacturing processes. Obtaining real-time information from processes opens new perspectives […]

Raman as a Process Analytical Technology (PAT) tool

raman as a process analytical technology (PAT) tool

Process Analytical Technology (PAT) has quickly become an integral component within the pharmaceutical and chemical manufacturing industries, providing timely quantitative measurements throughout production to measure critical quality attributes and parameters. In October 2004, the U.S. Food & Drug Administration (FDA) announced a Process Analytical Technology (PAT) approach for pharmaceutical manufacturers in their Guidance for Industry […]

Choosing the right laser for Raman spectroscopy

choosing the right laser for raman spectroscopy

In recent years, Raman spectroscopy has become a valuable tool in qualitative and quantitative chemical analysis for process analysis as the technology offers convenient in-situ sampling interfaces, continuous in-line measurements, and high spectral specificity. Raman is used across a range of industries including pharmaceuticals, oil & gas, bio processing, specialty chemical, food and beverage process […]

High Purity New England Supports Drug Development Pipelines with Fully Customizable and Flexible Single-Use Assembly Solution

HPNE supports drug development pipelines with fully customizable and flexible single use assembly solution

Demand for single-use assembly solutions in the biopharma industry continues to increase, with the market expected to be worth $26.89 billion by 20251 . To help meet that demand High Purity New England (HPNE), a leading supplier of biopharma equipment and process solutions for the biopharma industry, created HPConnexx, a single-use assembly solution suitable for […]

Dissolved CO2 Measurement in Cell Culture: Integrating an Inline CO2 Sensor

CO2 as a metabolic indicator Impact of CO2 on Extracellular and Intracellular pH Dissolved Carbon Dioxide Measurement & Control It has become industry practice to keep a close watch and refined control on pH and dissolved O2, in conjunction with parameters including pressure, temperature, and aeration rates. We’ve also seen a growing necessity to monitor […]