Perfusion Bioreactor

The Sunflower Therapeutics Daisy Petal™ perfusion bioreactor system is the first fermentation system designed and built for continuous protein production by fermentation experts.

This breakthrough capability means it can produce as much protein as a bigger reactor for a fraction of the size and cost.

Additionally, the system is designed for accessibility. Sunflower’s intuitive single-use assemblies include a perfusion-enabled bioreactor with all necessary sensors, filters, connections, and tubing attached to a rigid panel. Every component is mounted where it needs to be, empowering non-expert users to intuitively install the single-use tubing assembly on the Daisy Petal. Operations are fully automated by HelianthOS™, Sunflower’s universal operating system.

The Daisy Petal allows users to test key process parameters more efficiently, collect more data in one campaign, or simply produce greater quantities of cells or proteins.

Daisy Petal

Perfusion Bioreactor with Software
The Daisy Petal is Sunflower’s pioneering benchtop automated single-use bioreactor system for continuous protein, molecule or cell line production using microbes. Daisy Petal is designed to help you achieve your R&D goals in drug/vaccine development, food technologies, synthetic biology or diagnostics development, without being a bioprocessing expert.

‘Plug-N’-Produce’™ features include a structured single-use bioreactor assembly for successful installation every time, comprehensive “hands-free” system automation by HelianthOS and a simple cloud-based application, Nursery™, for building your recipe and monitoring its progress during operation on the Daisy Petal.

Key Benefits

Works continuously for you

Daisy Petal uses our patented in-vessel cell retention device and operates perfusion or chemostat fermentations

Maximize yields, minimize footprint

The 1L working volume of Daisy Petal can deliver up to 20L of output process fluids in one operation

Set up fast and properly

Intuitive layout and structured consumables mean no more installing tubing backwards

Process monitoring is standard

Daisy Petal systems and single-use assemblies come with ready-to-use sensors for pH, dissolved oxygen, temperature, and off-gas monitoring

Automated from start to finish

Sunflower’s universal HelianthOS software handles all the process controls and makes smart responses to deviations during a run. Remote and comprehensive process monitoring means you can walk away during Daisy Petal operations (it’s OK…go have lunch)

Easy to program

Sunflower’s cloud-based Nursery application lets you create recipes for the fermentation you want, from routine production to an efficient Design of Experiments (DoE)

It’s all in the box

Daisy Petal™ comes with all the hardware and software you need right in the box to get started immediately (that’s right — no extra parts to source or install before you get going.)

Use Cases & Applications